Members of the F-box protein family, such as FBXW10, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603034), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CDRT1-20-RE | 20 (40 μL) | 200 μL |  |
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| CDRT1-20-OR | 20 (40 μL) | 200 μL |  |
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| CDRT1-20-GO | 20 (40 μL) | 200 μL |  |
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| CDRT1-20-GR | 20 (40 μL) | 200 μL |  |
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| CDRT1-20-AQ | 20 (40 μL) | 200 μL |  |
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Members of the F-box protein family, such as FBXW10, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603034), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]
Gene Symbol : CDRT1
Gene Name : CMT1A duplicated region transcript 1
Chromosome : CHR 17: 156,197,03-155,654,81
Locus : 17p12
Alt. Genes : RCL1
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