Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. This gene may play a role in myotonic dystrophy type 1 (DM1) via interactions with the dystrophia myotonica-protein kinase (DMPK) gene. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CELF1-20-RE | 20 (40 μL) | 200 μL |  |
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| CELF1-20-OR | 20 (40 μL) | 200 μL |  |
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| CELF1-20-GO | 20 (40 μL) | 200 μL |  |
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| CELF1-20-GR | 20 (40 μL) | 200 μL |  |
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| CELF1-20-AQ | 20 (40 μL) | 200 μL |  |
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Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. This gene may play a role in myotonic dystrophy type 1 (DM1) via interactions with the dystrophia myotonica-protein kinase (DMPK) gene. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Symbol : CELF1
Gene Name : CUGBP Elav-like family member 1
Chromosome : CHR 11: 475,655,68-474,659,36
Locus : 11p11.2
Alt. Genes : RBM12
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