Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. This gene encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. Centromere protein A is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. The protein is a replication-independent histone that is a member of the histone H3 family. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Nov 2015]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CENPA-20-RE | 20 (40 μL) | 200 μL |  |
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| CENPA-20-OR | 20 (40 μL) | 200 μL |  |
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| CENPA-20-GO | 20 (40 μL) | 200 μL |  |
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| CENPA-20-GR | 20 (40 μL) | 200 μL |  |
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| CENPA-20-AQ | 20 (40 μL) | 200 μL |  |
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Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. This gene encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. Centromere protein A is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. The protein is a replication-independent histone that is a member of the histone H3 family. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Nov 2015]
Gene Symbol : CENPA
Gene Name : Centromere protein A
Chromosome : CHR 2: 267,860,13-267,945,88
Locus : 2p23.3
Alt. Genes : FAM13A
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