This gene encodes a centromere protein that is a component of the CENPA-NAC (nucleosome-associated) complex. This complex is critical for accurate chromosome alignment and segregation and it ensures proper mitotic progression. This protein regulates the recruitment of kinetochore-associated proteins that are required to generate the spindle checkpoint signal. The product of this gene is involved in the response of gonadal tissues to follicle-stimulating hormone. Mutations in this gene may be involved in human X-linked disorders of gonadal development and gametogenesis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 13. [provided by RefSeq, Jan 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CENPI-20-RE | 20 (40 μL) | 200 μL |  |
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| CENPI-20-OR | 20 (40 μL) | 200 μL |  |
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| CENPI-20-GO | 20 (40 μL) | 200 μL |  |
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| CENPI-20-GR | 20 (40 μL) | 200 μL |  |
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| CENPI-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a centromere protein that is a component of the CENPA-NAC (nucleosome-associated) complex. This complex is critical for accurate chromosome alignment and segregation and it ensures proper mitotic progression. This protein regulates the recruitment of kinetochore-associated proteins that are required to generate the spindle checkpoint signal. The product of this gene is involved in the response of gonadal tissues to follicle-stimulating hormone. Mutations in this gene may be involved in human X-linked disorders of gonadal development and gametogenesis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 13. [provided by RefSeq, Jan 2016]
Gene Symbol : CENPI
Gene Name : Centromere protein I
Chromosome : CHR X: 101,098,158-101,181,846
Locus : Xq22.1
Alt. Genes : SGK2
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