This gene encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome. [provided by RefSeq, Oct 2009]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CFHR1-20-RE | 20 (40 μL) | 200 μL |  |
Request Pricing |
| CFHR1-20-OR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| CFHR1-20-GO | 20 (40 μL) | 200 μL |  |
Request Pricing |
| CFHR1-20-GR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| CFHR1-20-AQ | 20 (40 μL) | 200 μL |  |
Request Pricing |
This gene encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome. [provided by RefSeq, Oct 2009]
Gene Symbol : CFHR1
Gene Name : Complement factor H related 1
Chromosome : CHR 1: 196,819,729-196,832,188
Locus : 1q31.3
Lorem Ipsum is simply dummy text of the printing and typesetting industry.
Lorem Ipsum is simply dummy text of the printing and typesetting industry.