Chromatin assembly factor I (CAF-I) is required for the assembly of histone octamers onto newly-replicated DNA. CAF-I is composed of three protein subunits, p50, p60, and p150. The protein encoded by this gene corresponds to the p60 subunit and is required for chromatin assembly after replication. The encoded protein is differentially phosphorylated in a cell cycle-dependent manner. In addition, it is normally found in the nucleus except during mitosis, when it is released into the cytoplasm. This protein is a member of the WD-repeat HIR1 family and may also be involved in DNA repair. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CHAF1B-20-RE | 20 (40 μL) | 200 μL |  |
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| CHAF1B-20-OR | 20 (40 μL) | 200 μL |  |
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| CHAF1B-20-GO | 20 (40 μL) | 200 μL |  |
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| CHAF1B-20-GR | 20 (40 μL) | 200 μL |  |
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| CHAF1B-20-AQ | 20 (40 μL) | 200 μL |  |
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Chromatin assembly factor I (CAF-I) is required for the assembly of histone octamers onto newly-replicated DNA. CAF-I is composed of three protein subunits, p50, p60, and p150. The protein encoded by this gene corresponds to the p60 subunit and is required for chromatin assembly after replication. The encoded protein is differentially phosphorylated in a cell cycle-dependent manner. In addition, it is normally found in the nucleus except during mitosis, when it is released into the cytoplasm. This protein is a member of the WD-repeat HIR1 family and may also be involved in DNA repair. [provided by RefSeq, Jul 2008]
Gene Symbol : CHAF1B
Gene Name : Chromatin assembly factor 1 subunit B
Chromosome : CHR 21: 363,801,44-364,168,26
Locus : 21q22.12-q22.13
Alt. Genes : ENAM
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