This gene encodes an E3 ubiquitin-protein ligase required for the maintenance of the antephase checkpoint that regulates cell cycle entry into mitosis and, therefore, may play a key role in cell cycle progression and tumorigenesis. The encoded protein has an N-terminal forkhead-associated domain, a central RING-finger domain, and a cysteine-rich C-terminal region. Alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq, Mar 2014]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CHFR-20-RE | 20 (40 μL) | 200 μL |  |
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| CHFR-20-OR | 20 (40 μL) | 200 μL |  |
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| CHFR-20-GO | 20 (40 μL) | 200 μL |  |
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| CHFR-20-GR | 20 (40 μL) | 200 μL |  |
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| CHFR-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes an E3 ubiquitin-protein ligase required for the maintenance of the antephase checkpoint that regulates cell cycle entry into mitosis and, therefore, may play a key role in cell cycle progression and tumorigenesis. The encoded protein has an N-terminal forkhead-associated domain, a central RING-finger domain, and a cysteine-rich C-terminal region. Alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq, Mar 2014]
Gene Symbol : CHFR
Gene Name : Checkpoint with forkhead and ring finger domains
Chromosome : CHR 12: 132,887,617-132,840,351
Locus : 12q24.33
Alt. Genes : FEM1B
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