Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Several alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jan 2012]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CHIT1-20-RE | 20 (40 μL) | 200 μL |  |
Request Pricing |
| CHIT1-20-OR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| CHIT1-20-GO | 20 (40 μL) | 200 μL |  |
Request Pricing |
| CHIT1-20-GR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| CHIT1-20-AQ | 20 (40 μL) | 200 μL |  |
Request Pricing |
Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Several alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jan 2012]
Gene Symbol : CHIT1
Gene Name : Chitinase 1
Chromosome : CHR 1: 203,229,731-203,216,078
Locus : 1q32.1
Alt. Genes : ZNF197
Lorem Ipsum is simply dummy text of the printing and typesetting industry.
Lorem Ipsum is simply dummy text of the printing and typesetting industry.