This gene encodes a protein that sorts transmembrane proteins into lysosomes/vacuoles via the multivesicular body (MVB) pathway. This protein, along with other soluble coiled-coil containing proteins, forms part of the ESCRT-III protein complex that binds to the endosomal membrane and recruits additional cofactors for protein sorting into the MVB. This protein may also co-immunoprecipitate with a member of the IFG-binding protein superfamily. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ring finger protein 103 (RNF103) gene. [provided by RefSeq, Nov 2010]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CHMP3-20-RE | 20 (40 μL) | 200 μL |  |
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| CHMP3-20-OR | 20 (40 μL) | 200 μL |  |
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| CHMP3-20-GO | 20 (40 μL) | 200 μL |  |
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| CHMP3-20-GR | 20 (40 μL) | 200 μL |  |
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| CHMP3-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a protein that sorts transmembrane proteins into lysosomes/vacuoles via the multivesicular body (MVB) pathway. This protein, along with other soluble coiled-coil containing proteins, forms part of the ESCRT-III protein complex that binds to the endosomal membrane and recruits additional cofactors for protein sorting into the MVB. This protein may also co-immunoprecipitate with a member of the IFG-binding protein superfamily. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ring finger protein 103 (RNF103) gene. [provided by RefSeq, Nov 2010]
Gene Symbol : CHMP3
Gene Name : Charged multivesicular body protein 3
Chromosome : CHR 2: 865,634,96-865,034,29
Locus : 2p11.2
Alt. Genes : ABI2
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