CHMP4A belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).[supplied by OMIM, Mar 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CHMP4A-20-RE | 20 (40 μL) | 200 μL |  |
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| CHMP4A-20-OR | 20 (40 μL) | 200 μL |  |
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| CHMP4A-20-GO | 20 (40 μL) | 200 μL |  |
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| CHMP4A-20-GR | 20 (40 μL) | 200 μL |  |
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| CHMP4A-20-AQ | 20 (40 μL) | 200 μL |  |
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CHMP4A belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).[supplied by OMIM, Mar 2008]
Gene Symbol : CHMP4A
Gene Name : Charged multivesicular body protein 4A
Chromosome : CHR 14: 242,138,29-242,095,80
Locus : 14q12
Alt. Genes : FSTL3
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