This gene encodes an alpha subunit of neuronal nicotinic acetylcholine receptors. These receptors consist of five subunits and function as ion channels involved in neurotransmission. The encoded protein is a subunit of neuronal nicotinic acetylcholine receptors that mediate dopaminergic neurotransmission and are activated by acetylcholine and exogenous nicotine. Alternatively spliced transcript variants have been observed for this gene. Single nucleotide polymorphisms in this gene have been associated with both nicotine and alcohol dependence. [provided by RefSeq, Dec 2010]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CHRNA6-20-RE | 20 (40 μL) | 200 μL |  |
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| CHRNA6-20-OR | 20 (40 μL) | 200 μL |  |
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| CHRNA6-20-GO | 20 (40 μL) | 200 μL |  |
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| CHRNA6-20-GR | 20 (40 μL) | 200 μL |  |
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| CHRNA6-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes an alpha subunit of neuronal nicotinic acetylcholine receptors. These receptors consist of five subunits and function as ion channels involved in neurotransmission. The encoded protein is a subunit of neuronal nicotinic acetylcholine receptors that mediate dopaminergic neurotransmission and are activated by acetylcholine and exogenous nicotine. Alternatively spliced transcript variants have been observed for this gene. Single nucleotide polymorphisms in this gene have been associated with both nicotine and alcohol dependence. [provided by RefSeq, Dec 2010]
Gene Symbol : CHRNA6
Gene Name : Cholinergic receptor nicotinic alpha 6 subunit
Chromosome : CHR 8: 427,687,85-427,526,19
Locus : 8p11.21
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