CHRNE FISH Probe

Acetylcholine receptors at mature mammalian neuromuscular junctions are pentameric protein complexes composed of four subunits in the ratio of two alpha subunits to one beta, one epsilon, and one delta subunit. The acetylcholine receptor changes subunit composition shortly after birth when the epsilon subunit replaces the gamma subunit seen in embryonic receptors. Mutations in the epsilon subunit are associated with congenital myasthenic syndrome. [provided by RefSeq, Sep 2009]


Gene Details
SKU Test Kits Buffer Dye Color Order Now
CHRNE-20-RE 20 (40 μL) 200 μL color Request Pricing
CHRNE-20-OR 20 (40 μL) 200 μL color Request Pricing
CHRNE-20-GO 20 (40 μL) 200 μL color Request Pricing
CHRNE-20-GR 20 (40 μL) 200 μL color Request Pricing
CHRNE-20-AQ 20 (40 μL) 200 μL color Request Pricing

Gene Summary

Acetylcholine receptors at mature mammalian neuromuscular junctions are pentameric protein complexes composed of four subunits in the ratio of two alpha subunits to one beta, one epsilon, and one delta subunit. The acetylcholine receptor changes subunit composition shortly after birth when the epsilon subunit replaces the gamma subunit seen in embryonic receptors. Mutations in the epsilon subunit are associated with congenital myasthenic syndrome. [provided by RefSeq, Sep 2009]

Gene Details

Gene Symbol : CHRNE

Gene Name : Cholinergic receptor nicotinic epsilon subunit

Chromosome : CHR 17: 490,501,8-489,776,8

Locus : 17p13.2

Alt. Genes : PLXNC1

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