This gene encodes a member of the Clp1 family. The encoded protein is a multifunctional kinase which is a component of the tRNA splicing endonuclease complex and a component of the pre-mRNA cleavage complex II. This protein is implicated in tRNA, mRNA, and siRNA maturation. Mutations in this gene are associated with pontocerebellar hypoplasia type 10 (PCH10). Alternatively splice transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CLP1-20-RE | 20 (40 μL) | 200 μL |  |
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| CLP1-20-OR | 20 (40 μL) | 200 μL |  |
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| CLP1-20-GO | 20 (40 μL) | 200 μL |  |
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| CLP1-20-GR | 20 (40 μL) | 200 μL |  |
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| CLP1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the Clp1 family. The encoded protein is a multifunctional kinase which is a component of the tRNA splicing endonuclease complex and a component of the pre-mRNA cleavage complex II. This protein is implicated in tRNA, mRNA, and siRNA maturation. Mutations in this gene are associated with pontocerebellar hypoplasia type 10 (PCH10). Alternatively splice transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]
Gene Symbol : CLP1
Gene Name : Cleavage and polyadenylation factor I subunit 1
Chromosome : CHR 11: 576,577,43-576,618,64
Locus : 11q12.1
Alt. Genes : OPTN
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