CMBL (EC 3.1.1.45) is a cysteine hydrolase of the dienelactone hydrolase family that is highly expressed in liver cytosol. CMBL preferentially cleaves cyclic esters, and it activates medoxomil-ester prodrugs in which the medoxomil moiety is linked to an oxygen atom (Ishizuka et al., 2010 [PubMed 20177059]).[supplied by OMIM, Apr 2010]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CMBL-20-RE | 20 (40 μL) | 200 μL |  |
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| CMBL-20-OR | 20 (40 μL) | 200 μL |  |
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| CMBL-20-GO | 20 (40 μL) | 200 μL |  |
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| CMBL-20-GR | 20 (40 μL) | 200 μL |  |
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| CMBL-20-AQ | 20 (40 μL) | 200 μL |  |
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CMBL (EC 3.1.1.45) is a cysteine hydrolase of the dienelactone hydrolase family that is highly expressed in liver cytosol. CMBL preferentially cleaves cyclic esters, and it activates medoxomil-ester prodrugs in which the medoxomil moiety is linked to an oxygen atom (Ishizuka et al., 2010 [PubMed 20177059]).[supplied by OMIM, Apr 2010]
Gene Symbol : CMBL
Gene Name : Carboxymethylenebutenolidase homolog
Chromosome : CHR 5: 103,080,55-102,775,94
Locus : 5p15.2
Alt. Genes : PREB
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