The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The encoded protein downregulates the innate immune response and therefore provides a therapeutic target for enhancing its antimicrobial activity against foreign agents. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and X. [provided by RefSeq, Apr 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CNOT7-20-RE | 20 (40 μL) | 200 μL |  |
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| CNOT7-20-OR | 20 (40 μL) | 200 μL |  |
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| CNOT7-20-GO | 20 (40 μL) | 200 μL |  |
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| CNOT7-20-GR | 20 (40 μL) | 200 μL |  |
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| CNOT7-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The encoded protein downregulates the innate immune response and therefore provides a therapeutic target for enhancing its antimicrobial activity against foreign agents. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and X. [provided by RefSeq, Apr 2016]
Gene Symbol : CNOT7
Gene Name : CCR4-NOT transcription complex subunit 7
Chromosome : CHR 8: 172,469,08-172,260,29
Locus : 8p22
Alt. Genes : ZNF263
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