Targeting of numerous transmembrane proteins to the cell surface is thought to depend on their recognition by cargo receptors that interact with the adaptor machinery for anterograde traffic at the distal end of the Golgi complex. Consortin (CNST) is an integral membrane protein that acts as a binding partner of connexins, the building blocks of gap junctions, and acts as a trans-Golgi network (TGN) receptor involved in connexin targeting to the plasma membrane and recycling from the cell surface (del Castillo et al., 2010 [PubMed 19864490]).[supplied by OMIM, Jun 2010]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
CNST-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
CNST-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
CNST-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
CNST-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
CNST-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
Targeting of numerous transmembrane proteins to the cell surface is thought to depend on their recognition by cargo receptors that interact with the adaptor machinery for anterograde traffic at the distal end of the Golgi complex. Consortin (CNST) is an integral membrane protein that acts as a binding partner of connexins, the building blocks of gap junctions, and acts as a trans-Golgi network (TGN) receptor involved in connexin targeting to the plasma membrane and recycling from the cell surface (del Castillo et al., 2010 [PubMed 19864490]).[supplied by OMIM, Jun 2010]
Gene Symbol : CNST
Gene Name : Consortin, connexin sorting protein
Chromosome : CHR 1: 246,566,336-246,668,586
Locus : 1q44
Alt. Genes : SUGP2
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