The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| COIL-20-RE | 20 (40 μL) | 200 μL |  |
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| COIL-20-OR | 20 (40 μL) | 200 μL |  |
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| COIL-20-GO | 20 (40 μL) | 200 μL |  |
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| COIL-20-GR | 20 (40 μL) | 200 μL |  |
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| COIL-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14. [provided by RefSeq, Jul 2008]
Gene Symbol : COIL
Gene Name : Coilin
Chromosome : CHR 17: 569,610,49-569,381,98
Locus : 17q22
Alt. Genes : OPTN
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