This gene encodes the alpha chain of type XV collagen, a member of the FACIT collagen family (fibril-associated collagens with interrupted helices). Type XV collagen has a wide tissue distribution but the strongest expression is localized to basement membrane zones so it may function to adhere basement membranes to underlying connective tissue stroma. The proteolytically produced C-terminal fragment of type XV collagen is restin, a potentially antiangiogenic protein that is closely related to endostatin. Mouse studies have shown that collagen XV deficiency is associated with muscle and microvessel deterioration. [provided by RefSeq, May 2013]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| COL15A1-20-RE | 20 (40 μL) | 200 μL |  |
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| COL15A1-20-OR | 20 (40 μL) | 200 μL |  |
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| COL15A1-20-GO | 20 (40 μL) | 200 μL |  |
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| COL15A1-20-GR | 20 (40 μL) | 200 μL |  |
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| COL15A1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes the alpha chain of type XV collagen, a member of the FACIT collagen family (fibril-associated collagens with interrupted helices). Type XV collagen has a wide tissue distribution but the strongest expression is localized to basement membrane zones so it may function to adhere basement membranes to underlying connective tissue stroma. The proteolytically produced C-terminal fragment of type XV collagen is restin, a potentially antiangiogenic protein that is closely related to endostatin. Mouse studies have shown that collagen XV deficiency is associated with muscle and microvessel deterioration. [provided by RefSeq, May 2013]
Gene Symbol : COL15A1
Gene Name : Collagen type XV alpha 1 chain
Chromosome : CHR 9: 989,433,91-990,707,91
Locus : 9q22.33
Alt. Genes : LRPPRC
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