This gene encodes a member of the collectin family of C-type lectins that possess collagen-like sequences and carbohydrate recognition domains. Collectins are secreted proteins that play important roles in the innate immune system by binding to carbohydrate antigens on microorganisms, facilitating their recognition and removal. The encoded protein binds to multiple sugars with a preference for fucose and mannose. Mutations in this gene are a cause of 3MC syndrome-2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| COLEC11-20-RE | 20 (40 μL) | 200 μL |  |
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| COLEC11-20-OR | 20 (40 μL) | 200 μL |  |
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| COLEC11-20-GO | 20 (40 μL) | 200 μL |  |
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| COLEC11-20-GR | 20 (40 μL) | 200 μL |  |
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| COLEC11-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the collectin family of C-type lectins that possess collagen-like sequences and carbohydrate recognition domains. Collectins are secreted proteins that play important roles in the innate immune system by binding to carbohydrate antigens on microorganisms, facilitating their recognition and removal. The encoded protein binds to multiple sugars with a preference for fucose and mannose. Mutations in this gene are a cause of 3MC syndrome-2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
Gene Symbol : COLEC11
Gene Name : Collectin subfamily member 11
Chromosome : CHR 2: 359,483,1-364,464,3
Locus : 2p25.3
Alt. Genes : PREB
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