This gene encodes a member of the coronin protein family. However, unlike other coronin proteins, it is not an actin-binding protein but rather functions as an F-actin regulator directing anterograde Golgi to endosome transport. The encoded protein has two tandem WD-40 domain repeats and localizes to the trans-Golgi network. The protein undergoes K33-linked polyubiquitination via an E3 ligase complex. It is thought to play an essential role in maintenance of Golgi apparatus morphology. Alternative splicing results in multiple transcripts variants; some of which form read-through transcripts with a neighboring gene. [provided by RefSeq, Dec 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CORO7-20-RE | 20 (40 μL) | 200 μL |  |
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| CORO7-20-OR | 20 (40 μL) | 200 μL |  |
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| CORO7-20-GO | 20 (40 μL) | 200 μL |  |
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| CORO7-20-GR | 20 (40 μL) | 200 μL |  |
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| CORO7-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the coronin protein family. However, unlike other coronin proteins, it is not an actin-binding protein but rather functions as an F-actin regulator directing anterograde Golgi to endosome transport. The encoded protein has two tandem WD-40 domain repeats and localizes to the trans-Golgi network. The protein undergoes K33-linked polyubiquitination via an E3 ligase complex. It is thought to play an essential role in maintenance of Golgi apparatus morphology. Alternative splicing results in multiple transcripts variants; some of which form read-through transcripts with a neighboring gene. [provided by RefSeq, Dec 2016]
Gene Symbol : CORO7
Gene Name : Coronin 7
Chromosome : CHR 16: 441,696,0-435,454,1
Locus : 16p13.3
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