This gene encodes one of the numerous actin-binding proteins which regulate the actin cytoskeleton. This protein binds F-actin, and also interacts with 5-lipoxygenase, which is the first committed enzyme in leukotriene biosynthesis. Although this gene has been reported to map to chromosome 17 in the Smith-Magenis syndrome region, the best alignments for this gene are to chromosome 16. The Smith-Magenis syndrome region is the site of two related pseudogenes. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| COTL1-20-RE | 20 (40 μL) | 200 μL |  |
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| COTL1-20-OR | 20 (40 μL) | 200 μL |  |
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| COTL1-20-GO | 20 (40 μL) | 200 μL |  |
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| COTL1-20-GR | 20 (40 μL) | 200 μL |  |
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| COTL1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes one of the numerous actin-binding proteins which regulate the actin cytoskeleton. This protein binds F-actin, and also interacts with 5-lipoxygenase, which is the first committed enzyme in leukotriene biosynthesis. Although this gene has been reported to map to chromosome 17 in the Smith-Magenis syndrome region, the best alignments for this gene are to chromosome 16. The Smith-Magenis syndrome region is the site of two related pseudogenes. [provided by RefSeq, Jul 2008]
Gene Symbol : COTL1
Gene Name : Coactosin like F-actin binding protein 1
Chromosome : CHR 16: 846,180,95-845,655,95
Locus : 16q24.1
Alt. Genes : ENAM
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