Carboxypeptidase N is a plasma metallo-protease that cleaves basic amino acids from the C terminal of peptides and proteins. The enzyme is important in the regulation of peptides like kinins and anaphylatoxins, and has also been known as kininase-1 and anaphylatoxin inactivator. This enzyme is a tetramer comprised of two identical regulatory subunits and two identical catalytic subunits; this gene encodes the catalytic subunit. Mutations in this gene can be associated with angioedema or chronic urticaria resulting from carboxypeptidase N deficiency. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CPN1-20-RE | 20 (40 μL) | 200 μL |  |
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| CPN1-20-OR | 20 (40 μL) | 200 μL |  |
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| CPN1-20-GO | 20 (40 μL) | 200 μL |  |
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| CPN1-20-GR | 20 (40 μL) | 200 μL |  |
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| CPN1-20-AQ | 20 (40 μL) | 200 μL |  |
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Carboxypeptidase N is a plasma metallo-protease that cleaves basic amino acids from the C terminal of peptides and proteins. The enzyme is important in the regulation of peptides like kinins and anaphylatoxins, and has also been known as kininase-1 and anaphylatoxin inactivator. This enzyme is a tetramer comprised of two identical regulatory subunits and two identical catalytic subunits; this gene encodes the catalytic subunit. Mutations in this gene can be associated with angioedema or chronic urticaria resulting from carboxypeptidase N deficiency. [provided by RefSeq, Jul 2008]
Gene Symbol : CPN1
Gene Name : Carboxypeptidase N subunit 1
Chromosome : CHR 10: 100,081,884-100,042,307
Locus : 10q24.2
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