The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
CPT1A-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
CPT1A-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
CPT1A-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
CPT1A-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
CPT1A-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Symbol : CPT1A
Gene Name : Carnitine palmitoyltransferase 1A
Chromosome : CHR 11: 688,444,09-687,546,19
Locus : 11q13.3
Alt. Genes : FARP1
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