Corticotropin-releasing hormone is a potent stimulator of synthesis and secretion of preopiomelanocortin-derived peptides. Although CRH concentrations in the human peripheral circulation are normally low, they increase throughout pregnancy and fall rapidly after parturition. Maternal plasma CRH probably originates from the placenta. Human plasma contains a CRH-binding protein which inactivates CRH and which may prevent inappropriate pituitary-adrenal stimulation in pregnancy. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CRHBP-20-RE | 20 (40 μL) | 200 μL |  |
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| CRHBP-20-OR | 20 (40 μL) | 200 μL |  |
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| CRHBP-20-GO | 20 (40 μL) | 200 μL |  |
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| CRHBP-20-GR | 20 (40 μL) | 200 μL |  |
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| CRHBP-20-AQ | 20 (40 μL) | 200 μL |  |
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Corticotropin-releasing hormone is a potent stimulator of synthesis and secretion of preopiomelanocortin-derived peptides. Although CRH concentrations in the human peripheral circulation are normally low, they increase throughout pregnancy and fall rapidly after parturition. Maternal plasma CRH probably originates from the placenta. Human plasma contains a CRH-binding protein which inactivates CRH and which may prevent inappropriate pituitary-adrenal stimulation in pregnancy. [provided by RefSeq, Jul 2008]
Gene Symbol : CRHBP
Gene Name : Corticotropin releasing hormone binding protein
Chromosome : CHR 5: 769,527,12-769,811,42
Locus : 5q13.3
Alt. Genes : ENAM
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