This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.[provided by RefSeq, Jan 2009]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CRKL-20-RE | 20 (40 μL) | 200 μL |  |
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| CRKL-20-OR | 20 (40 μL) | 200 μL |  |
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| CRKL-20-GO | 20 (40 μL) | 200 μL |  |
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| CRKL-20-GR | 20 (40 μL) | 200 μL |  |
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| CRKL-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.[provided by RefSeq, Jan 2009]
Gene Symbol : CRKL
Gene Name : CRK like proto-oncogene, adaptor protein
Chromosome : CHR 22: 209,173,97-209,537,48
Locus : 22q11.21
Alt. Genes : TRAP1
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