This gene encodes a cytokine receptor-like factor that may negatively regulate cell cycle progression at the G0/G1 phase. Studies of the related rat protein suggest that it may regulate neuronal morphology and synaptic vesicle biogenesis. This gene is one of several genes located in the neurofibromatosis type I tumor suppressor region on the q arm of chromosome 17, a region that is subject to microdeletions, duplications, chromosomal breaks and rearrangements. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 2 and 5. [provided by RefSeq, Aug 2012]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CRLF3-20-RE | 20 (40 μL) | 200 μL |  |
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| CRLF3-20-OR | 20 (40 μL) | 200 μL |  |
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| CRLF3-20-GO | 20 (40 μL) | 200 μL |  |
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| CRLF3-20-GR | 20 (40 μL) | 200 μL |  |
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| CRLF3-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a cytokine receptor-like factor that may negatively regulate cell cycle progression at the G0/G1 phase. Studies of the related rat protein suggest that it may regulate neuronal morphology and synaptic vesicle biogenesis. This gene is one of several genes located in the neurofibromatosis type I tumor suppressor region on the q arm of chromosome 17, a region that is subject to microdeletions, duplications, chromosomal breaks and rearrangements. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 2 and 5. [provided by RefSeq, Aug 2012]
Gene Symbol : CRLF3
Gene Name : Cytokine receptor like factor 3
Chromosome : CHR 17: 308,247,59-307,826,83
Locus : 17q11.2
Alt. Genes : RAD50
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