This gene is a member of the CREB regulated transcription coactivator gene family. This family regulates CREB-dependent gene transcription in a phosphorylation-independent manner and may be selective for cAMP-responsive genes. The protein encoded by this gene may induce mitochondrial biogenesis and attenuate catecholamine signaling in adipose tissue. A translocation event between this gene and Notch coactivator mastermind-like gene 2, which results in a fusion protein, has been reported in mucoepidermoid carcinomas. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CRTC3-20-RE | 20 (40 μL) | 200 μL |  |
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| CRTC3-20-OR | 20 (40 μL) | 200 μL |  |
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| CRTC3-20-GO | 20 (40 μL) | 200 μL |  |
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| CRTC3-20-GR | 20 (40 μL) | 200 μL |  |
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| CRTC3-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene is a member of the CREB regulated transcription coactivator gene family. This family regulates CREB-dependent gene transcription in a phosphorylation-independent manner and may be selective for cAMP-responsive genes. The protein encoded by this gene may induce mitochondrial biogenesis and attenuate catecholamine signaling in adipose tissue. A translocation event between this gene and Notch coactivator mastermind-like gene 2, which results in a fusion protein, has been reported in mucoepidermoid carcinomas. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012]
Gene Symbol : CRTC3
Gene Name : CREB regulated transcription coactivator 3
Chromosome : CHR 15: 905,298,85-906,453,44
Locus : 15q26.1
Alt. Genes : ABI2
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