This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Loss of the related gene in mouse results in a shortened circadian cycle in complete darkness. [provided by RefSeq, Jan 2014]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CRY1-20-RE | 20 (40 μL) | 200 μL |  |
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| CRY1-20-OR | 20 (40 μL) | 200 μL |  |
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| CRY1-20-GO | 20 (40 μL) | 200 μL |  |
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| CRY1-20-GR | 20 (40 μL) | 200 μL |  |
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| CRY1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Loss of the related gene in mouse results in a shortened circadian cycle in complete darkness. [provided by RefSeq, Jan 2014]
Gene Symbol : CRY1
Gene Name : Cryptochrome circadian regulator 1
Chromosome : CHR 12: 107,093,871-106,991,363
Locus : 12q23.3
Alt. Genes : OPTN
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