The protein encoded by this gene catalyzes the formation of CTP from UTP with the concomitant deamination of glutamine to glutamate. This protein is the rate-limiting enzyme in the synthesis of cytosine nucleotides, which play an important role in various metabolic processes and provide the precursors necessary for the synthesis of RNA and DNA. Cancer cells that exhibit increased cell proliferation also exhibit an increased activity of this encoded protein. Thus, this protein is an attractive target for selective chemotherapy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CTPS2-20-RE | 20 (40 μL) | 200 μL |  |
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| CTPS2-20-OR | 20 (40 μL) | 200 μL |  |
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| CTPS2-20-GO | 20 (40 μL) | 200 μL |  |
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| CTPS2-20-GR | 20 (40 μL) | 200 μL |  |
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| CTPS2-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene catalyzes the formation of CTP from UTP with the concomitant deamination of glutamine to glutamate. This protein is the rate-limiting enzyme in the synthesis of cytosine nucleotides, which play an important role in various metabolic processes and provide the precursors necessary for the synthesis of RNA and DNA. Cancer cells that exhibit increased cell proliferation also exhibit an increased activity of this encoded protein. Thus, this protein is an attractive target for selective chemotherapy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Gene Symbol : CTPS2
Gene Name : CTP synthase 2
Chromosome : CHR X: 167,129,78-165,879,98
Locus : Xp22.2
Alt. Genes : CLEC3A
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