This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. Alternative promoter use and alternative splicing results in multiple transcript variants that have different tissue specificities. [provided by RefSeq, Dec 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CYP19A1-20-RE | 20 (40 μL) | 200 μL |  |
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| CYP19A1-20-OR | 20 (40 μL) | 200 μL |  |
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| CYP19A1-20-GO | 20 (40 μL) | 200 μL |  |
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| CYP19A1-20-GR | 20 (40 μL) | 200 μL |  |
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| CYP19A1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. Alternative promoter use and alternative splicing results in multiple transcript variants that have different tissue specificities. [provided by RefSeq, Dec 2016]
Gene Symbol : CYP19A1
Gene Name : Cytochrome P450 family 19 subfamily A member 1
Chromosome : CHR 15: 513,385,97-512,080,56
Locus : 15q21.2
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