This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CYP46A1-20-RE | 20 (40 μL) | 200 μL |  |
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| CYP46A1-20-OR | 20 (40 μL) | 200 μL |  |
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| CYP46A1-20-GO | 20 (40 μL) | 200 μL |  |
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| CYP46A1-20-GR | 20 (40 μL) | 200 μL |  |
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| CYP46A1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism. [provided by RefSeq, Jul 2008]
Gene Symbol : CYP46A1
Gene Name : Cytochrome P450 family 46 subfamily A member 1
Chromosome : CHR 14: 996,842,61-997,273,20
Locus : 14q32.2
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