The protein encoded by this gene is a ligand-dependent coactivator of nuclear receptors, including nuclear receptor subfamily 3 group C member 1 (NR3C1), glucocorticoid receptor (GR), and androgen receptor (AR). The encoded protein and DNA damage binding protein 2 (DDB2) may act as tumor promoters and tumor suppressors, respectively, by regulating the level of androgen receptor in prostate tissues. In addition, this protein can act with glucocorticoid receptor to promote human papillomavirus gene expression. [provided by RefSeq, Mar 2017]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DCAF6-20-RE | 20 (40 μL) | 200 μL |  |
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| DCAF6-20-OR | 20 (40 μL) | 200 μL |  |
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| DCAF6-20-GO | 20 (40 μL) | 200 μL |  |
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| DCAF6-20-GR | 20 (40 μL) | 200 μL |  |
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| DCAF6-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a ligand-dependent coactivator of nuclear receptors, including nuclear receptor subfamily 3 group C member 1 (NR3C1), glucocorticoid receptor (GR), and androgen receptor (AR). The encoded protein and DNA damage binding protein 2 (DDB2) may act as tumor promoters and tumor suppressors, respectively, by regulating the level of androgen receptor in prostate tissues. In addition, this protein can act with glucocorticoid receptor to promote human papillomavirus gene expression. [provided by RefSeq, Mar 2017]
Gene Symbol : DCAF6
Gene Name : DDB1 and CUL4 associated factor 6
Chromosome : CHR 1: 167,936,246-168,075,842
Locus : 1q24.2
Alt. Genes : LRPPRC
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