This antimicrobial gene encodes a secreted protein that is subsequently processed into mature peptides of distinct biological activities. The C-terminal peptide is constitutively expressed in sweat and has antibacterial and antifungal activities. The N-terminal peptide, also known as diffusible survival evasion peptide, promotes neural cell survival under conditions of severe oxidative stress. A glycosylated form of the N-terminal peptide may be associated with cachexia (muscle wasting) in cancer patients. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2014]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DCD-20-RE | 20 (40 μL) | 200 μL |  |
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| DCD-20-OR | 20 (40 μL) | 200 μL |  |
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| DCD-20-GO | 20 (40 μL) | 200 μL |  |
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| DCD-20-GR | 20 (40 μL) | 200 μL |  |
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| DCD-20-AQ | 20 (40 μL) | 200 μL |  |
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This antimicrobial gene encodes a secreted protein that is subsequently processed into mature peptides of distinct biological activities. The C-terminal peptide is constitutively expressed in sweat and has antibacterial and antifungal activities. The N-terminal peptide, also known as diffusible survival evasion peptide, promotes neural cell survival under conditions of severe oxidative stress. A glycosylated form of the N-terminal peptide may be associated with cachexia (muscle wasting) in cancer patients. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2014]
Gene Symbol : DCD
Gene Name : Dermcidin
Chromosome : CHR 12: 546,484,92-546,445,90
Locus : 12q13.2
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