DCLRE1C FISH Probe

This gene encodes a nuclear protein that is involved in V(D)J recombination and DNA repair. The encoded protein has single-strand-specific 5'-3' exonuclease activity; it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins. The protein also functions in the regulation of the cell cycle in response to DNA damage. Mutations in this gene can cause Athabascan-type severe combined immunodeficiency (SCIDA) and Omenn syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]


Gene Details
SKU Test Kits Buffer Dye Color Order Now
DCLRE1C-20-RE 20 (40 μL) 200 μL color Request Pricing
DCLRE1C-20-OR 20 (40 μL) 200 μL color Request Pricing
DCLRE1C-20-GO 20 (40 μL) 200 μL color Request Pricing
DCLRE1C-20-GR 20 (40 μL) 200 μL color Request Pricing
DCLRE1C-20-AQ 20 (40 μL) 200 μL color Request Pricing

Gene Summary

This gene encodes a nuclear protein that is involved in V(D)J recombination and DNA repair. The encoded protein has single-strand-specific 5'-3' exonuclease activity; it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins. The protein also functions in the regulation of the cell cycle in response to DNA damage. Mutations in this gene can cause Athabascan-type severe combined immunodeficiency (SCIDA) and Omenn syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

Gene Details

Gene Symbol : DCLRE1C

Gene Name : DNA cross-link repair 1C

Chromosome : CHR 10: 149,544,31-148,978,52

Locus : 10p13

Alt. Genes : RBM12

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