This gene encodes a component of the oligosaccharyltransferase complex which catalyzes the transfer of high-mannose oligosaccharides to asparagine residues on nascent polypeptides in the lumen of the rough endoplasmic reticulum. The protein complex co-purifies with ribosomes. The product of this gene is also implicated in the processing of advanced glycation endproducts (AGEs), which form from non-enzymatic reactions between sugars and proteins or lipids and are associated with aging and hyperglycemia. [provided by RefSeq, Jul 2008]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
DDOST-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
DDOST-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
DDOST-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
DDOST-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
DDOST-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
This gene encodes a component of the oligosaccharyltransferase complex which catalyzes the transfer of high-mannose oligosaccharides to asparagine residues on nascent polypeptides in the lumen of the rough endoplasmic reticulum. The protein complex co-purifies with ribosomes. The product of this gene is also implicated in the processing of advanced glycation endproducts (AGEs), which form from non-enzymatic reactions between sugars and proteins or lipids and are associated with aging and hyperglycemia. [provided by RefSeq, Jul 2008]
Gene Symbol : DDOST
Gene Name : Dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit
Chromosome : CHR 1: 206,615,43-206,517,66
Locus : 1p36.12
Alt. Genes : KIF20A
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