This gene encodes a member of the discoidin domain receptor subclass of the receptor tyrosine kinase (RTKs) protein family. RTKs play a key role in the communication of cells with their microenvironment. The encoded protein is a collagen-induced receptor that activates signal transduction pathways involved in cell adhesion, proliferation, and extracellular matrix remodeling. This protein is expressed in numerous cell types and may alos be involved in wound repair and regulate tumor growth and invasiveness. Mutations in this gene are the cause of short limb-hand type spondylometaepiphyseal dysplasia. [provided by RefSeq, Aug 2017]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
DDR2-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
DDR2-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
DDR2-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
DDR2-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
DDR2-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
This gene encodes a member of the discoidin domain receptor subclass of the receptor tyrosine kinase (RTKs) protein family. RTKs play a key role in the communication of cells with their microenvironment. The encoded protein is a collagen-induced receptor that activates signal transduction pathways involved in cell adhesion, proliferation, and extracellular matrix remodeling. This protein is expressed in numerous cell types and may alos be involved in wound repair and regulate tumor growth and invasiveness. Mutations in this gene are the cause of short limb-hand type spondylometaepiphyseal dysplasia. [provided by RefSeq, Aug 2017]
Gene Symbol : DDR2
Gene Name : Discoidin domain receptor tyrosine kinase 2
Chromosome : CHR 1: 162,631,212-162,783,523
Locus : 1q23.3
Alt. Genes : FEM1B
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