This gene encodes a protein that contains a death effector domain (DED). DED is a protein-protein interaction domain shared by adaptors, regulators and executors of the programmed cell death pathway. Overexpression of this gene was shown to induce weak apoptosis. Upon stimulation, this protein was found to translocate from cytoplasm to nucleus and colocalize with UBTF, a basal factor required for RNA polymerase I transcription, in the nucleolus. At least three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DEDD-20-RE | 20 (40 μL) | 200 μL |  |
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| DEDD-20-OR | 20 (40 μL) | 200 μL |  |
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| DEDD-20-GO | 20 (40 μL) | 200 μL |  |
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| DEDD-20-GR | 20 (40 μL) | 200 μL |  |
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| DEDD-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a protein that contains a death effector domain (DED). DED is a protein-protein interaction domain shared by adaptors, regulators and executors of the programmed cell death pathway. Overexpression of this gene was shown to induce weak apoptosis. Upon stimulation, this protein was found to translocate from cytoplasm to nucleus and colocalize with UBTF, a basal factor required for RNA polymerase I transcription, in the nucleolus. At least three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Symbol : DEDD
Gene Name : Death effector domain containing
Chromosome : CHR 1: 161,132,782-161,120,976
Locus : 1q23.3
Alt. Genes : AKAP9
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