Defensins form a family of antimicrobial and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions. Chromosome 8p23 contains at least two copies of the duplicated beta-defensin cluster. This duplication results in two identical copies of defensin, beta 105, DEFB105A and DEFB105B, in tail-to-tail orientation. This gene, DEFB105B, represents the more telomeric copy. [provided by RefSeq, Oct 2014]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DEFB105B-20-RE | 20 (40 μL) | 200 μL |  |
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| DEFB105B-20-OR | 20 (40 μL) | 200 μL |  |
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| DEFB105B-20-GO | 20 (40 μL) | 200 μL |  |
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| DEFB105B-20-GR | 20 (40 μL) | 200 μL |  |
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| DEFB105B-20-AQ | 20 (40 μL) | 200 μL |  |
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Defensins form a family of antimicrobial and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions. Chromosome 8p23 contains at least two copies of the duplicated beta-defensin cluster. This duplication results in two identical copies of defensin, beta 105, DEFB105A and DEFB105B, in tail-to-tail orientation. This gene, DEFB105B, represents the more telomeric copy. [provided by RefSeq, Oct 2014]
Gene Symbol : DEFB105B
Gene Name : Defensin beta 105B
Chromosome : CHR 8: 748,766,8-748,959,2
Locus : 8p23.1
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