Defensins form a family of antimicrobial and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions. The protein encoded by this gene is a beta-defensin with antimicrobial activity against E. coli, S. aureus, and C. albicans. The encoded protein also binds and neutralizes lipopolysaccharide (LPS), a factor involved in inflammatory diseases and male reproductive issues. [provided by RefSeq, Nov 2014]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DEFB114-20-RE | 20 (40 μL) | 200 μL |  |
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| DEFB114-20-OR | 20 (40 μL) | 200 μL |  |
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| DEFB114-20-GO | 20 (40 μL) | 200 μL |  |
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| DEFB114-20-GR | 20 (40 μL) | 200 μL |  |
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| DEFB114-20-AQ | 20 (40 μL) | 200 μL |  |
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Defensins form a family of antimicrobial and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions. The protein encoded by this gene is a beta-defensin with antimicrobial activity against E. coli, S. aureus, and C. albicans. The encoded protein also binds and neutralizes lipopolysaccharide (LPS), a factor involved in inflammatory diseases and male reproductive issues. [provided by RefSeq, Nov 2014]
Gene Symbol : DEFB114
Gene Name : Defensin beta 114
Chromosome : CHR 6: 499,641,04-499,602,91
Locus : 6p12.3
Alt. Genes : SPIN1
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