This gene encodes a member of the membrane fatty acid desaturase family which is responsible for inserting double bonds into specific positions in fatty acids. This protein contains three His-containing consensus motifs that are characteristic of a group of membrane fatty acid desaturases. It is predicted to be a multiple membrane-spanning protein localized to the endoplasmic reticulum. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor. [provided by RefSeq, Mar 2010]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DEGS1-20-RE | 20 (40 μL) | 200 μL |  |
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| DEGS1-20-OR | 20 (40 μL) | 200 μL |  |
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| DEGS1-20-GO | 20 (40 μL) | 200 μL |  |
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| DEGS1-20-GR | 20 (40 μL) | 200 μL |  |
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| DEGS1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the membrane fatty acid desaturase family which is responsible for inserting double bonds into specific positions in fatty acids. This protein contains three His-containing consensus motifs that are characteristic of a group of membrane fatty acid desaturases. It is predicted to be a multiple membrane-spanning protein localized to the endoplasmic reticulum. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor. [provided by RefSeq, Mar 2010]
Gene Symbol : DEGS1
Gene Name : Delta 4-desaturase, sphingolipid 1
Chromosome : CHR 1: 224,183,207-224,193,440
Locus : 1q42.11
Alt. Genes : OPTN
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