The protein encoded by this gene functions as a guanine nucleotide exchange factor for the early endosomal small GTPase RAB35, which regulates endosomal membrane trafficking and is involved in actin polymerization. The encoded protein activates RAB35 by promoting the exchange of RAB35-bound GDP for GTP. This gene may play a role in linking RAB35 activation with the clathrin machinery. [provided by RefSeq, May 2017]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DENND1C-20-RE | 20 (40 μL) | 200 μL |  |
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| DENND1C-20-OR | 20 (40 μL) | 200 μL |  |
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| DENND1C-20-GO | 20 (40 μL) | 200 μL |  |
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| DENND1C-20-GR | 20 (40 μL) | 200 μL |  |
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| DENND1C-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene functions as a guanine nucleotide exchange factor for the early endosomal small GTPase RAB35, which regulates endosomal membrane trafficking and is involved in actin polymerization. The encoded protein activates RAB35 by promoting the exchange of RAB35-bound GDP for GTP. This gene may play a role in linking RAB35 activation with the clathrin machinery. [provided by RefSeq, May 2017]
Gene Symbol : DENND1C
Gene Name : DENN domain containing 1C
Chromosome : CHR 19: 648,180,7-646,720,3
Locus : 19p13.3
Alt. Genes : TRIM28
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