This gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double-stranded RNA binding protein that functions as the non-catalytic subunit of the microprocessor complex. This protein is required for binding the double-stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein, Drosha. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DGCR8-20-RE | 20 (40 μL) | 200 μL |  |
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| DGCR8-20-OR | 20 (40 μL) | 200 μL |  |
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| DGCR8-20-GO | 20 (40 μL) | 200 μL |  |
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| DGCR8-20-GR | 20 (40 μL) | 200 μL |  |
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| DGCR8-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double-stranded RNA binding protein that functions as the non-catalytic subunit of the microprocessor complex. This protein is required for binding the double-stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein, Drosha. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
Gene Symbol : DGCR8
Gene Name : DGCR8, microprocessor complex subunit
Chromosome : CHR 22: 200,802,31-201,118,76
Locus : 22q11.21
Alt. Genes : KIF20A
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