This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. This protein demonstrates oxidoreductase activity toward hydroxysteroids and is able to convert 3-alpha-tetrahydroprogesterone to dihydroxyprogesterone and 3-alpha-androstanediol to dihydroxyprogesterone in the cytoplasm, and may additionally function as a transcriptional repressor in the nucleus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DHRS9-20-RE | 20 (40 μL) | 200 μL |  |
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| DHRS9-20-OR | 20 (40 μL) | 200 μL |  |
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| DHRS9-20-GO | 20 (40 μL) | 200 μL |  |
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| DHRS9-20-GR | 20 (40 μL) | 200 μL |  |
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| DHRS9-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. This protein demonstrates oxidoreductase activity toward hydroxysteroids and is able to convert 3-alpha-tetrahydroprogesterone to dihydroxyprogesterone and 3-alpha-androstanediol to dihydroxyprogesterone in the cytoplasm, and may additionally function as a transcriptional repressor in the nucleus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Gene Symbol : DHRS9
Gene Name : Dehydrogenase/reductase 9
Chromosome : CHR 2: 169,067,034-169,096,166
Locus : 2q31.1
Alt. Genes : CEBPZ
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