The pattern of cellular proliferation and differentiation that leads to normal development of embryonic structures often depends upon the localized production of secreted protein signals. Cells surrounding the source of a particular signal respond in a graded manner according to the effective concentration of the signal, and this response produces the pattern of cell types constituting the mature structure. A novel segment-polarity gene known as dispatched has been identified in Drosophila and its protein product is required for normal Hedgehog (Hh) signaling. This gene is one of two human homologs of Drosophila dispatched and, based on sequence identity to its mouse counterpart, the encoded protein may play an essential role in Hh patterning activities in the early embryo. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DISP1-20-RE | 20 (40 μL) | 200 μL |  |
Request Pricing |
| DISP1-20-OR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| DISP1-20-GO | 20 (40 μL) | 200 μL |  |
Request Pricing |
| DISP1-20-GR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| DISP1-20-AQ | 20 (40 μL) | 200 μL |  |
Request Pricing |
The pattern of cellular proliferation and differentiation that leads to normal development of embryonic structures often depends upon the localized production of secreted protein signals. Cells surrounding the source of a particular signal respond in a graded manner according to the effective concentration of the signal, and this response produces the pattern of cell types constituting the mature structure. A novel segment-polarity gene known as dispatched has been identified in Drosophila and its protein product is required for normal Hedgehog (Hh) signaling. This gene is one of two human homologs of Drosophila dispatched and, based on sequence identity to its mouse counterpart, the encoded protein may play an essential role in Hh patterning activities in the early embryo. [provided by RefSeq, Jul 2008]
Gene Symbol : DISP1
Gene Name : Dispatched RND transporter family member 1
Chromosome : CHR 1: 222,814,513-223,005,994
Locus : 1q41
Alt. Genes : FEM1B
Lorem Ipsum is simply dummy text of the printing and typesetting industry.
Lorem Ipsum is simply dummy text of the printing and typesetting industry.