This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. It can act as either an agonist or antagonist of Wnt/beta-catenin signaling, depending on the cellular context and the presence of the co-factor kremen 2. Activity of this protein is also modulated by binding to the Wnt co-receptor LDL-receptor related protein 6 (LRP6). [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DKK2-20-RE | 20 (40 μL) | 200 μL |  |
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| DKK2-20-OR | 20 (40 μL) | 200 μL |  |
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| DKK2-20-GO | 20 (40 μL) | 200 μL |  |
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| DKK2-20-GR | 20 (40 μL) | 200 μL |  |
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| DKK2-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. It can act as either an agonist or antagonist of Wnt/beta-catenin signaling, depending on the cellular context and the presence of the co-factor kremen 2. Activity of this protein is also modulated by binding to the Wnt co-receptor LDL-receptor related protein 6 (LRP6). [provided by RefSeq, Jul 2008]
Gene Symbol : DKK2
Gene Name : Dickkopf WNT signaling pathway inhibitor 2
Chromosome : CHR 4: 107,036,295-106,921,801
Locus : 4q25
Alt. Genes : PREB
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