This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DMRT1-20-RE | 20 (40 μL) | 200 μL |  |
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| DMRT1-20-OR | 20 (40 μL) | 200 μL |  |
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| DMRT1-20-GO | 20 (40 μL) | 200 μL |  |
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| DMRT1-20-GR | 20 (40 μL) | 200 μL |  |
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| DMRT1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous. [provided by RefSeq, Jul 2008]
Gene Symbol : DMRT1
Gene Name : Doublesex and mab-3 related transcription factor 1
Chromosome : CHR 9: 841,646-969,089
Locus : 9p24.3
Alt. Genes : TRAP1
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