This gene encodes a member of the DNA2/NAM7 helicase family. The encoded protein is a conserved helicase/nuclease involved in the maintenance of mitochondrial and nuclear DNA stability. Mutations in this gene are associated with autosomal dominant progressive external ophthalmoplegia-6 (PEOA6) and Seckel syndrome 8. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2014]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DNA2-20-RE | 20 (40 μL) | 200 μL |  |
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| DNA2-20-OR | 20 (40 μL) | 200 μL |  |
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| DNA2-20-GO | 20 (40 μL) | 200 μL |  |
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| DNA2-20-GR | 20 (40 μL) | 200 μL |  |
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| DNA2-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the DNA2/NAM7 helicase family. The encoded protein is a conserved helicase/nuclease involved in the maintenance of mitochondrial and nuclear DNA stability. Mutations in this gene are associated with autosomal dominant progressive external ophthalmoplegia-6 (PEOA6) and Seckel syndrome 8. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2014]
Gene Symbol : DNA2
Gene Name : DNA replication helicase/nuclease 2
Chromosome : CHR 10: 684,725,20-684,140,63
Locus : 10q21.3
Alt. Genes : ZNF263
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