CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. [provided by RefSeq, Mar 2016]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
DNMT3A-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
DNMT3A-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
DNMT3A-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
DNMT3A-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
DNMT3A-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. [provided by RefSeq, Mar 2016]
Gene Symbol : DNMT3A
Gene Name : DNA methyltransferase 3 alpha
Chromosome : CHR 2: 253,425,89-252,329,60
Locus : 2p23.3
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