This gene encodes a member of the dedicator of cytokinesis (DOCK) family of atypical guanine nucleotide exchange factors. Guanine nucleotide exchange factors interact with small GTPases and are components of intracellular signaling networks. The encoded protein is a group C DOCK protein and plays a role in actin cytoskeletal reorganization by activating the Rho GTPases Cdc42 and Rac1. Mutations in this gene are associated with Adams-Oliver syndrome 2. [provided by RefSeq, Dec 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DOCK6-20-RE | 20 (40 μL) | 200 μL |  |
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| DOCK6-20-OR | 20 (40 μL) | 200 μL |  |
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| DOCK6-20-GO | 20 (40 μL) | 200 μL |  |
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| DOCK6-20-GR | 20 (40 μL) | 200 μL |  |
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| DOCK6-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the dedicator of cytokinesis (DOCK) family of atypical guanine nucleotide exchange factors. Guanine nucleotide exchange factors interact with small GTPases and are components of intracellular signaling networks. The encoded protein is a group C DOCK protein and plays a role in actin cytoskeletal reorganization by activating the Rho GTPases Cdc42 and Rac1. Mutations in this gene are associated with Adams-Oliver syndrome 2. [provided by RefSeq, Dec 2011]
Gene Symbol : DOCK6
Gene Name : Dedicator of cytokinesis 6
Chromosome : CHR 19: 112,625,01-111,992,92
Locus : 19p13.2
Alt. Genes : ATP6AP2
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