This gene encodes a member of the DOCK180 family of guanine nucleotide exchange factors. Guanine nucleotide exchange factors interact with Rho GTPases and are components of intracellular signaling networks. Mutations in this gene result in the autosomal recessive form of the hyper-IgE syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Jun 2010]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DOCK8-20-RE | 20 (40 μL) | 200 μL |  |
Request Pricing |
| DOCK8-20-OR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| DOCK8-20-GO | 20 (40 μL) | 200 μL |  |
Request Pricing |
| DOCK8-20-GR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| DOCK8-20-AQ | 20 (40 μL) | 200 μL |  |
Request Pricing |
This gene encodes a member of the DOCK180 family of guanine nucleotide exchange factors. Guanine nucleotide exchange factors interact with Rho GTPases and are components of intracellular signaling networks. Mutations in this gene result in the autosomal recessive form of the hyper-IgE syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Jun 2010]
Gene Symbol : DOCK8
Gene Name : Dedicator of cytokinesis 8
Chromosome : CHR 9: 211,296-465,259
Locus : 9p24.3
Alt. Genes : PREB
Lorem Ipsum is simply dummy text of the printing and typesetting industry.
Lorem Ipsum is simply dummy text of the printing and typesetting industry.